Fig. 1

Multivariable adjusted relative risk of all-cause mortality (A) and MACCE (B) according to physical activity levels as classified in the Physical Activity Guidelines. ^†Minimum key guidelines target range in Physical Activity Guidelines for Americans by the U.S. Department of Health and Human Services (2018): Doing the equivalent of 500–1,000 MET-min/week of physical activity. ^‡Multivariable adjusted hazard ratio: age, sex, body mass index, heart failure, hypertension, diabetes, previous myocardial infarction, prior stroke or transient ischemic attack, chronic kidney disease, dyslipidemia, smoking, and alcohol intake. CI, confidence interval; MACCE, major adverse cardiac and cerebrovascular events; MET, metabolic equivalent task